Prescribing Information, including Boxed WARNING                          For Healthcare Professionals
IMPORTANT SAFETY INFORMATION for AVANDIA® (rosiglitazone maleate)
AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart), you cannot be started on AVANDIA (see Boxed WARNING).
SAFETY INFORMATION CONTINUED BELOW 
AVANDIA rosiglitazone maleate | Diabetes Medication
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AVANDIA With Other Type 2 Diabetes Medicines

AVANDIA can be taken alone or with other type 2 diabetes medicines. It works differently from some other type 2 diabetes medicines. AVANDIA does not cause your body to make more insulin instead, AVANDIA helps the body use its own natural insulin better -- for improved blood sugar control.*

AVANDIA, along with diet and exercise, can be taken alone or in combination with other diabetes pills to help improve blood sugar control - but taking AVANDIA when using insulin or nitrates is not recommended.

Most people with type 2 diabetes take medicine to help keep their blood sugar under control. Many people take more than one medicine to help treat diabetes in different ways. In fact, it can be a helpful way to help you control your blood sugar. Your body and your diabetes change over time.

Two type 2 diabetes medicines, one pill

  • We know that when you're managing type 2 diabetes, there's a lot to think about. So if you're taking AVANDIA plus another type 2 diabetes medicine, you might be looking for a way to make things simpler. One way is taking AVANDIA plus another diabetes medicine in just one pill instead of two pills.

    These "combination" medicines can make it more convenient for people who take more than one medicine to help treat their diabetes in different ways. If you are taking AVANDIA plus one of these other type 2 diabetes medicines, talk to your doctor about whether you could reduce the number of pills you take to 1 combination medicine, rather than 2 separate pills.

    *Individual results may vary.

 

*Only your doctor can decide if AVANDIA is right for you. AVANDIA is not right for everyone.
Taking AVANDIA with insulin or nitrates is not recommended.

IMPORTANT SAFETY INFORMATION for AVANDIA® (rosiglitazone maleate)

AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart) you cannot be started on AVANDIA. AVANDIA is also not recommended if you have heart failure with symptoms (such as shortness of breath or swelling), even if these symptoms are not severe.

AVANDIA may increase your risk of other heart problems that occur when there is reduced blood flow to the heart, such as chest pain (angina) or heart attack (myocardial infarction). This risk appeared higher in patients taking medicines called nitrates or insulin.

If you have chest pain or a feeling of chest pressure, you should seek immediate medical attention, regardless of what diabetes medicines you are taking. If you take AVANDIA, tell your doctor right away if you have swollen legs or ankles, a rapid increase in weight or difficulty breathing, or unusual tiredness; experience changes in vision; become pregnant.

Before taking AVANDIA, review your medical history and tell your doctor if you:

Women taking AVANDIA should know that AVANDIA may increase the risk of pregnancy. More fractures have been observed in women taking AVANDIA. Other possible side effects of AVANDIA include anemia and hypoglycemia. Your doctor should do blood tests to check your liver before you start AVANDIA and during treatment as needed.

Prescription AVANDIA, along with diet and exercise, helps improve blood sugar control in adults with type 2 diabetes.

For more information about AVANDIA, please see Medication Guide and full Prescribing Information, including Boxed WARNING.