Prescribing Information, including Boxed WARNING                          For Healthcare Professionals
IMPORTANT SAFETY INFORMATION for AVANDIA® (rosiglitazone maleate)
AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart), you cannot be started on AVANDIA (see Boxed WARNING).
SAFETY INFORMATION CONTINUED BELOW 
AVANDIA rosiglitazone maleate | Diabetes Medication
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Stay Active

In addition to healthy eating, regular physical activity is very important for people with diabetes. Just 30 minutes a day of activity (even in three 10-minute bursts) can help you manage your diabetes. So you can get physical while you clean, shop, garden, or take the stairs. You should talk to your doctor first about which physical activities are right for you.

Choose something you enjoy doing

There are lots of activities you can do around your home to burn calories. You don't have to join a gym or run a marathon to see results. Choose something you like and stay with it. Read these tips on some physical activities you may enjoy.

Regular physical activity can help:

  • Manage your weight
  • Improve your blood pressure
  • Strengthen your heart
  • Improve blood circulation
  • Improve cholesterol
  • Improve your body's response to insulin
  • Lower blood sugar levels

Seven ways to stay active

  1. Take the stairs instead of the elevator.
  2. At work, take a walk with a co-worker to discuss ideas, instead of using the phone.
  3. Sightsee in new cities - or your own town - by walking or biking.
  4. Participate in a charity walk like those listed at www.diabetes.org.
  5. Volunteer to walk your neighbor's dog or sweep their sidewalk.
  6. Plan family outings that include hiking or swimming.
  7. Volunteer at a hospital, local school or library. It will keep you out and about - and moving.

Be sure to check your blood sugar levels before and after exercise. If you exercise for over 30 minutes, check your sugar during this activity. Remember to carry glucose tablets with you in case your blood sugar gets low.

Visit www.diabetes.com to learn more about how to stay active.

You should first talk to your doctor about which physical activities are right for you.

*Only your doctor can decide if AVANDIA is right for you. AVANDIA is not right for everyone.
Taking AVANDIA with insulin or nitrates is not recommended.

IMPORTANT SAFETY INFORMATION for AVANDIA® (rosiglitazone maleate)

AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart) you cannot be started on AVANDIA. AVANDIA is also not recommended if you have heart failure with symptoms (such as shortness of breath or swelling), even if these symptoms are not severe.

AVANDIA may increase your risk of other heart problems that occur when there is reduced blood flow to the heart, such as chest pain (angina) or heart attack (myocardial infarction). This risk appeared higher in patients taking medicines called nitrates or insulin.

If you have chest pain or a feeling of chest pressure, you should seek immediate medical attention, regardless of what diabetes medicines you are taking. If you take AVANDIA, tell your doctor right away if you have swollen legs or ankles, a rapid increase in weight or difficulty breathing, or unusual tiredness; experience changes in vision; become pregnant.

Before taking AVANDIA, review your medical history and tell your doctor if you:

Women taking AVANDIA should know that AVANDIA may increase the risk of pregnancy. More fractures have been observed in women taking AVANDIA. Other possible side effects of AVANDIA include anemia and hypoglycemia. Your doctor should do blood tests to check your liver before you start AVANDIA and during treatment as needed.

Prescription AVANDIA, along with diet and exercise, helps improve blood sugar control in adults with type 2 diabetes.

For more information about AVANDIA, please see Medication Guide and full Prescribing Information, including Boxed WARNING.