Prescribing Information, including Boxed WARNING                          For Healthcare Professionals
IMPORTANT SAFETY INFORMATION for AVANDIA® (rosiglitazone maleate)
AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart), you cannot be started on AVANDIA (see Boxed WARNING).
SAFETY INFORMATION CONTINUED BELOW 
AVANDIA rosiglitazone maleate | Diabetes Medication
Blood Sugar Levels
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Blood Sugar Levels

It’s important to know your blood sugar level goal. Use these blood sugar guidelines as a start to understanding your blood sugar level goals. Check with your doctor to find out the right blood sugar level for you.

Blood sugar guidelines: What the numbers mean

Blood sugar level What the number means
Above 180 mg/dL If your number is greater than 180 mg/dL one to two hours after you start a meal, your diabetes is not under control.

If you have high blood sugar (hyperglycemia) many times a week, call your doctor. Talk about your blood sugar levels. You may need a check-up, or a change in your treatment.
Above 130 mg/dL If your number is greater than 130 mg/dL before a meal, your diabetes is not under control.

If you have high blood sugar (hyperglycemia) many times a week, call your doctor. Talk about your blood sugar levels. You may need a check-up, or a change in your treatment.
70 to 130 mg/dL Aim for this “fasting” blood sugar range before you eat.
70 mg/dL or below
 This reading means you may have low blood sugar (hypoglycemia).

When you test your blood sugar at home, you can use the Blood Sugar Tracker (PDF) to write down your results.  Share your blood sugar control records with your doctor.

*Only your doctor can decide if AVANDIA is right for you. AVANDIA is not right for everyone.
Taking AVANDIA with insulin or nitrates is not recommended.

IMPORTANT SAFETY INFORMATION for AVANDIA® (rosiglitazone maleate)

AVANDIA can cause or worsen heart failure. If you have severe heart failure (very poor pumping ability of the heart) you cannot be started on AVANDIA. AVANDIA is also not recommended if you have heart failure with symptoms (such as shortness of breath or swelling), even if these symptoms are not severe.

AVANDIA may increase your risk of other heart problems that occur when there is reduced blood flow to the heart, such as chest pain (angina) or heart attack (myocardial infarction). This risk appeared higher in patients taking medicines called nitrates or insulin.

If you have chest pain or a feeling of chest pressure, you should seek immediate medical attention, regardless of what diabetes medicines you are taking. If you take AVANDIA, tell your doctor right away if you have swollen legs or ankles, a rapid increase in weight or difficulty breathing, or unusual tiredness; experience changes in vision; become pregnant.

Before taking AVANDIA, review your medical history and tell your doctor if you:

Women taking AVANDIA should know that AVANDIA may increase the risk of pregnancy. More fractures have been observed in women taking AVANDIA. Other possible side effects of AVANDIA include anemia and hypoglycemia. Your doctor should do blood tests to check your liver before you start AVANDIA and during treatment as needed.

Prescription AVANDIA, along with diet and exercise, helps improve blood sugar control in adults with type 2 diabetes.

For more information about AVANDIA, please see Medication Guide and full Prescribing Information, including Boxed WARNING.